Jerome H. Check, M.D., Ph.D.
Medical and Laboratory Director of IVF

CURRICULUM VITAE

EDUCATIONAL EXPERIENCE:

1. University of Pennsylvania, Biology, 1963 - 1967 

2. Hahnemann Medical College, 1967 - 1971 

3. Straight Medical Intern, Lankenau Hospital, Philadelphia, Pennsylvania, 1971 - 1972 

4. Resident in Internal Medicine, Lankenau Hospital, 1972 - 1974 

5. Fellow in Gynecologic Endocrinology, Jefferson Medical College and Hospital, 1974 - 1975

6. Ph.D. in Biological Sciences (OB/GYN). Department of Obstetrics and Gynecology Jagiellonian University College of Medicine, June 1997

MILITARY SERVICE:

United States Army Reserves, 1971 to 12/77, Captain 

Predominantly out-patient gynecology

PRIZES, AWARDS, HONORS:

1. Olney High School, Philadelphia, Pennsylvania, 1959 - 1963

  • A. Senior Superlatives, voted most intelligent in class
    •

      B. Phi Beta Kappa Award

    2. Full paid scholarship, University of Pennsylvania

      A. Honors major in Biology

    3. Full paid scholarship, Hahnemann Medical College

    4. Alpha Omega Alpha, Hahnemann Medical College

    5. Charles Ebberhardt Award for Cancer Research

    6. Jane Stuart Award for Clinical Oncology, Hahnemann Medical College 

    7. Honors - Internal Medicine

    8. Runner-up-James Ewing Society Award for Cancer Research, 1974

    9. Diplomate, American Board of Internal Medicine, 1974

    10. Associate Fellow of the American College of Obstetrics and Gynecology

    11. Fellow of the American College of Physicians

    12. Board Certified Endocrinology and Metabolism 1982

    13. Fellow of the American College of Clinical Endocrinology

    14. 25-year Professional Attainment Award, Hahnemann University School of Medicine

    PROFESSIONAL MEDICAL EXPERIENCE:

    1. Associated with Drs. Abraham Rakoff and Alvin Goldfarb, July 1975 - August, 1977, in the practice of gynecology endocrinology, infertility, and medical endocrinology.
    2. August, 1977 to present, practice of gynecologic endocrinology, infertility, and medical endocrinology.
    3. Instructor, Department of OB-GYN, 7/1/75-6/30/78, Division of Reproductive Endocrinology & Infertility, The Jefferson Medical College of Thomas Jefferson University Hospital.
    4. Assistant Professor, Department OB-GYN, 7/1/79-6/30/84, Division of Reproductive Endocrinology & Infertility, The Jefferson Medical College of Thomas Jefferson University Hospital.
    5. Associate Professor, Department OB-GYN, 7/1/84-8/89, Division of Reproductive Endocrinology & Infertility, The Jefferson Medical College of Thomas Jefferson University Hospital.
    6. Assistant Professor, Department of Medicine, 7/1/76-8/89, Division of Reproductive Endocrinology & Infertility, The Jefferson Medical College of Thomas Jefferson University Hospital.
    7. Methodist Hospital - On staff in the department of OB-GYN and consultant staff in the department of Medicine.
    8. Jeanes Hospital - On staff in the department of OB-GYN.
    9. Laboratory Director of Endocrine Testing, Ltd.
    10. Medical Director of the Cooper Center for IVF - 1991 to present
    11. Program Director of the Cooper Center for IVF - October 1993 to September 1995
    12. Professor of Clinical Obstetrics and Gynecology at the University of Medicine and Dentistry of New Jersey.
    13. Division Head, Division of Reproductive Endocrinology and Infertility, Robert ood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Camden, New Jersey.
    14. December, 1993 to present, Consultant, Department of Obstetrics and Gynecology, St. Francis Hospital, Wilmington, Delaware.

    Professional Societies

    1. American College of Physicians

    2. American Fertility Society

    3. The American College of Obstetricians and Gynecologists

    4. Endocrine Society

    5. American Association for the Advancement of Science

    6. Association of Professors of Gynecology and Obstetrics

    7. American Society for Bone and Mineral Research 

    8. American Society of Andrology

    9. The New York Academy of Sciences

    10. American Physicians Fellowship, Inc. for Medicine in Israel

    11. International Society of Gynecological Endocrinology

    12. American Association of Gynecologic Laparoscopists

    13. European Society of Human Reproduction and Embryology

    14. US International Foundation for Studies in Reproduction, Inc., Charter Associate Member

    15. International Society for the Immunology of Reproduction

    16. Montgomery County Medical Society

    17. Pacific Coast Fertility Society

    18. Philadelphia Area Reproductive Endocrine Society (P.A.R.E.S.)

    19. Member of National Infertility Network Exchange since 1994.

    JOURNAL EDITORIAL STAFF

    1. Editorial Review Board, USA

  • International Journal of Fertility 
    •

    2. Life Science Advances: General Endocrinology 

    3. Special reviewer for Obstetrics and Gynecology 

    4. Reviewer for Journal of Andrology

    5. International Editorial Board

  • Search Your Colleague's Practice on Obstetrics and Gynaecology
    •

    6. Reviewer for Journal of Assisted Reproduction and Genetics

    LECTURES AND SCIENTIFIC PRESENTATIONS:

    1. American Association for Cell Biology, San Diego, 1970.

  • "Studies of immunological protection against virally-induced mammary tumors of R III mice." 
    •

    2. American Association for Cancer Research, Chicago, 1971.

  • "Immunological protection against spontaneous mammary tumors in R III mice." 
    •

    3. American Association for Therapeutic Radiologists, Phoenix, 1972. 

    4. American Association for Cancer Research, Atlantic City, 1973.

  • "Decreased mumps sensitivity test in patients with breast cancer receiving mediastinal radiation." 
    •

    5. American Association for Therapeutic Radiologists, New Orleans, 1973.

  • "Diminished delayed hypersensitivity reactions in patients with lymphoma treated by radiation therapy by mantele technique." 
    •

    6. International Cancer Congress, Florence, Italy, 1974.

  • "Protection against transplanted and spontaneous lymphoma by inoculation of heat-altered syngeneic tumor cells in splenectomized mice." 
    •

    7. American Association for Cancer Research, Toronto, 1976.

  • "Immunologic protection against murine Hodgkins-like reticulum cell sarcoma."
    •

    8. American Fertility Society, New Orleans, March, 1978.

  • "Improved fertility in oligospermic males treated with clomiphene citrate." 
    •

    9. Pan American Conference on Fertility and Sterility, Acapulco, Mexico January, 1979.

  • "Improved semen quality in subfertile males with varicocele-associated oligospermia following treatment with clomiphene citrate."
    •

     10. Pan American Conference on Fertility and Sterility, Aruba, Netherlands, Antilles, March, 1980.

  • "Ovulation induction with Bromoergocryptine in patients with normal serum prolactin."
    •

    Open Forum Discussion

     11. World Conference on Embryo Transfer and Instrumental Insemination, Kiel, West Germany, September, 1980.

  • "Improved fertility results with split ejaculate insemination and improved cervical mucus."

    Chairman: Clinical aspects of instrumental insemination.

    •

     12. The New Jersey Obstetrical and Gynecological Society, Atlantic City, New Jersey, April 2, 1981.

  • "New approaches to the diagnosis and treatment of ovulation disorders."
    •

     13. Eastern Regional Meeting of the American College of Physicians, Hershey Pocono Resort, September 26, 1981.

  • "Idiopathic Edema as a common cause of inability to lose weight despite appropriate dieting."
    •

     14. Pan American Conference on Fertility and Sterility, Puerto Rico, February, 1982.

     15. Pan American Conference on Fertility and Sterility, Acapulco, Mexico, February, 1983.

    1. "Decreased abortions in hMG-induced pregnancies with prophylactic progesterone therapy."

    2. "The use of office ultrasound in infertility."

    3. "Improvement of cervical factor by high dose estrogen and hMG therapy with ultrasound monitoring."

    Panel Discussion Symposiums

    1. Induction of ovulation and ovum recovery.

    2. Can pelvic adhesions be prevented?

    16. Pan American Conference on Fertility and Sterility, Hawaii, February, 1984.

    1. "New approaches to the diagnosis and therapy of the luteinized unruptured follicle syndrome."

    2. "Employment of pelvic sonography in the diagnosis and treatment of the cervical factor."

    Panel Discussion Symposiums

     1. Induction of ovulation and ovum recovery.

    2. Menopausal problems.

    3. Contraception.

    17. The American College of Ob-Gyn District III, Bermuda, October, 1984.

  • "Idiopathic Edema may be a cause of recalcitrant obesity."
    •

    18. The Pan American Conference on Fertility and Sterility, Ixtapa, Mexico February, 1985.

  • 1. "Ovulation induction with hypergonadotropic amenorrhea with estrogen and hMG therapy."

    2. "Comparative safety and efficacy of pure follicle stimulating hormone versus human menopausal gonadotropins."

      Panel Discussion Symposium

    1. Estrogen-progesterone controversy.

    2. World population and fertility planning technologies - the next 20 years.

    •

    19. The American College of Obstetricians and Gynecologists, District III Meeting, Rome, Italy, September, 1985.

  • "Prophylactic use of progesterone to decrease abortions in high risk patients."
    •

    20. The American Fertility Society, Chicago, Illinois, September-October, 1985.

  • "Improved semen quality after a short interval second ejaculation."
    •

    21. The Pan American Conference on Fertility and Sterility, Acapulco, Mexico, February, 1986.

    1. "The efficiency of progesterone in achieving successful pregnancies in women with pure luteal phase defects."

    2. The treatment of cervical factor with ethinyl estradiol and human menopausal gonadotropins."

    3. "The use of pelvic sonography and serum estradiols and progesterone assays in the diagnosis and treatment of the cervical factor."

    4. "Spontaneous abortion rate in patients with endometriosis treated with progesterone."

    Panel discussion symposiums

    1. Pelvic factors in infertility.

    2. Update on the use of estrogens and progesterone.

    22. National Symposium on Prolactin Disorders, Marco Island, Florida April, 1986, Sandoz Symposium.

  • "Hyperprolactinemia and luteal phase defects."
    •

    23. XII World Congress on Fertility and Sterility, Republic of Singapore October, 1986.

    1. "The clinical usefulness of the hamster ova penetration test in unexplained infertility."

    2. "Combined use of pelvic sonography and serum estradiol (E2) and progesterone (P) assays in more precise monitoring of ovulation in infertility patients."

    3. "An in vivo technique for screening immunologic factors in infertility."

    24. The Pan American Conference on Fertility and Sterility, Puerto Rico, January, 1987.

  • "Progesterone therapy to decrease first trimester spontaneous abortions in previous aborters."
    •

    25. The American Society of Andrology, Denver, Colorado, March, 1987.

  • "An In Vivo Technique for screening immunologic factors in the etiology of the unexplained poor post coital test."
    •

    26. International Congress on Gynecological Endoscopy, IVF and Human Reproduction, Rio DeJaneiro, Brazil, June 7-11, 1987.

  • 1. "Luteal Phase Defects - New Techniques in Determining Therapy and the Role of Hyperprolactinemia."

    2. "Improved Fertility with Clomiphene Therapy of the Male with Normal Spermograms in Unexplained Infertility."

    3. "The Importance of Laparoscopic Coagulation of Mild Endometriosis in Infertile Women."

    •

    27. Fertility Research Foundation. Fourth World Conference: Infectious Diseases and Human Infertility. New York, March 26-27, 1987.

  • The importance of luteal phase deficiency as a cause of infertility in private practice - a preliminary report."
    •

    28. The American Fertility Society's Annual Meeting, Reno, Nevada, September 27-October 1, 1987.

  • 1. "Bromocriptine Versus Progesterone Therapy for Infertility Related to Luteal Phase Defects in Hyperprolactinemic Patients."

    2. "Ovulation Inducing Drugs Versus Progesterone Therapy for Infertility in Patients With Luteal Phase Defects".

    •

    29. VI World Congress on Human Reproduction, Tokyo, Japan, October, 1987.

  • 1. "A controlled study laparoscopic fulguration of stage 1 and 2 endometriosis in infertility."

    2. "Bromocriptine versus progesterone therapy for infertility related to luteal phase defects in hyperprolactinemic patients."?

    3. "Empirical therapy of the male with clomiphene citrate in couples with unexplained infertility."

    4. "Ovulation-inducing drugs versus progesterone therapy for infertility in patients with luteal phase defects."

    •

    30. The Pan American Conference on Fertility and Sterility, Hawaii, February, 1988.

  • 1. "An in-vivo technique for screening immunologic factors in the etiology of the unexplained poor post-coital test."

    2. "17 Hydroxyprogesterone levels as a marker for corpus luteum function in aborters versus non-aborters."

    3. "Therapeutic regimes to induce ovulation in women with ovarian failure."

    4. "Empirical therapy of the male with clomiphene in couples with unexplained infertility."

    Panel Discussion Symposiums

    1. Male infertility - what's really new?

    2. Stump the experts.

    3. Diseases affecting infertility.

    •

    31. Pacific Coast Fertility Society, Palm Springs, California, April, 1988.

  • "The clinical significance of the hypo-osmotic swelling (HOS) test."
    •

    32. 8th International Congress of Endocrinology, Kyoto, Japan, July, 1988.

  • 1. "The clinical correlation of the progestogen associated endometrial protein (PEP) with the endometrial biopsy."

    2. "Comparative clinical effect of spironolactone versus amphetamine for idiopathic orthostatic edema."

    •

    33. American Fertility Society, 44th Annual Meeting, Atlanta, Georgia, October, 1988.

  • 1. "The Clinical Correlation of the Progestogen Associated Endometrial Protein (PEP) with the Endometrial Biopsy."

    2. "Treatment of Luteinized Unruptured Follicle Syndrome in Infertility Patients."

    3. "Effect of Age on Infertility Therapy."

    •

    34. Dr. C.L. Jhaveri, I,F.R.P. oration award lecture on "Recent Advances Management of Infertility", November 26, 1988, Bombay, India.

    35. AIDS Awareness Conference, Key West, Florida, December, 1988.

  • Transmission of sexually transmitted diseases (STD) by donor semen."
    •

    36. Fifth World Conference on Infectious Diseases and Human Infertility, Cairo, Egypt, January 12-15, 1989.

  • "Failure of Positive Chlamydia Trachomatis Antibody Levels to Correlate with Infertility."
    •

    37. VI World Congress In Vitro Fertilization and Alternate Assisted Reproduction, Jerusalem, Israel, April, 1989.

  • 1. "CA-125 levels in in vitro fertilization-embryo transfer pregnancies versus natural pregnancies."

    2. "Correlation of computerized semen analysis and IVF-ET percent fertilization."

    3. "Results of in vitro fertilization-embryo transfer (IVF-ET) in women with ovarian failure."

    4. "Serum progestogen - associated endometrial protein (PEP) levels in conception versus non-conception cycles in patients undergoing in vitro fertilization-embryo transfer (IVF-ET)."

    5. "In vitro fertilization-embryo transfer for unexplained infertility (IVF-ET) - a unique case report."

    •

    38. International Meeting of Pregnancy Loss, Tel Aviv, Israel, April, 1989.

  • 1. "A challenge to the concept that spontaneous abortion is inevitable when the serum progesterone is less than 15 ng/ml.

    2. "Progesterone therapy to decrease spontaneous abortions."

    3. "Late first and early second trimester abortions in women demonstrating early first trimester elevations in CA-125."

    •

    39. American Society of Andrology 14th Annual Meeting, New Orleans, LA, April, 1989.

  • 1. "Addition of sperm free donor seminal plasma to low volume antegrade ejaculate in men with retrograde ejaculation."

    2. "Routine semen analysis versus computer automated semen analysis to predict male fertility potential."

    3. "The hypo-osmotic swelling test as an adjunct to the semen analysis as a prediction of fertility potential."

    •

    40. Pacific Coast Fertility Society, Palm Springs, Nevada, April, 1989.

  • "Treatment of cervical factor in infertility patients."
    •

    41. American Society for Medical Technology and the American Medical Technologists, King of Prussia, Pennsylvania, April, 1989.

  • "Immunologic Aspects of Infertility."
    •

    42. IV International Congress of Andrology, Florence, Italy, May, 1989.

  • 1. "Addition of sperm free donor seminal plasma to low volume antegrade ejaculate in men with retrograde ejaculation."

    2. "Routine semen analysis versus computer automated semen analysis to predict male fertility potential."

    3. "The hypo-osmotic swelling test as a useful adjunct to the semen analysis to predict fertility potential."

    •

    43. The American College of Obstetricians and Gynecologists, Annual Meeting, Atlanta, Georgia, May, 1989.

  • "Very high CA-125 level as a possible predictor of spontaneous abortion."
    •

    44. American Society for Medical Technology, 57th Annual Meeting and Exposition, Washington, DC, June, 1989.

  • "Elevated CA-125 levels in pregnancy."
    •

    45. European Society of Human Reproduction and Embryology, 5th Annual Meeting, Malmo-Copenhagen, June, 1989.

  • 1. "Pelvic sonography can predict ovum release in gonadotropin treated patients."

    2. "Measurement of serum progestogen associated endometrial protein (PEP) not helpful in predicting infertility or spontaneous abortion."

    •

    46. Assisted Reproductive Technology/Andrology, 2nd World Meeting, Casablanca, Morocco, September, 1989.

  • 1. "Non-invasive techniques for improving fertility potential of retrograde ejaculates."

    2. "Laboratory methods of achieving human sex preselection."

    3. "Evaluation and treatment of a male factor component to unexplained infertility."

    4. "Transmission of STD by donor semen."

    5. Workshop on advanced methods for evaluating semen.

    6. Workshop on methods of freezing embryos and spermatozoa.

    •

    47. XIII World Congress on Fertility and Sterility, IFFS 89, Marrakesh, Morocco, October, 1989.

  • 1. "Ovulation induction and pregnancies in women with ovarian failure."

    2. "The results of chlamydia trachomatis antibody testing should not influence patient/doctor decision on performing tubal studies."

    3. "A clinical evaluation of the PipelleR endometrial suction curette (Pipelle de CornierTM) for timed endometrial biopsies."

    4. "Ectopic pregnancy resulting from microsurgical fallopian tube transposition."

    5. "Low 17 hydroxy progesterone levels during first trimester predictive of spontaneous abortion."

    •

    48. American Fertility Society 45th Annual Meeting, November 11-16, 1989.

  • 1. "Premature luteinization in unstimulated cycles in infertile women and its treatment."

    2. "Male sex selection following swim-up technique and insemination in gonadotropin-treated women."

    3. "Pitfalls in the use of a single rapid progesterone assay to diagnose early ectopic pregnancies."

    •

    49. 33rd Pan American Conference on Fertility and Sterility, Dominican Republic, February 3-10, 1990.

  • 1. "Evaluation of the semen analysis in determining the role of male factor in infertility."

    2. "Elevated early first trimester CA-125 levels may be predictive of fetal anomalies."

    3. "Donor egg IVF versus attempts to induce ovulation in women with ovarian failure."

    4. "Influence of serum progesterone levels at the time of hCG on the release of ova during hMG cycles."

    •
  • Panel Discussion Symposiums

    1. Who should treat the infertile male?

    2. Quiz the experts.

    3. Who should be doing IVF-ET?

    4. Can "runaway" fertility therapy be reined in before it is rained out?

    Annual Symposium

     1. Quiz the experts.

    •

    50. Present and Future Reproduction, Naples, Italy, March 25-26, 1990.

  • 1. "Improved fertility rates for ovulation disorders may need to alter present methods of employing "fertility drugs."

    2. "New concepts and questions arising from an egg donation program."

    •

    51. American Society of Andrology 1990 Meeting, Columbia, South Carolina, April 6-9, 1990.

  • 1. "Computer assisted semen analysis parameters and hypo-osmotic swelling change with advancing age."

    2. "Comparison of fresh versus frozen donor seminal plasma for enhancing motility in asthenospermic semen samples."

    3. "Correlation of WHO grading system of motility versus linearity and velocity from computerized semen analysis (including prediction of fertility potential)."

    4. "Motile density not predictive of sperm fertilization potential as determined by pregnancies achieved using therapeutic insemination with donor."

    5. "Sperm morphology as a predictive of male fertility potential."

    •

    52. Pacific Coast Fertility Society 38th Annual Meeting, Scottsdale, Arizona, April 25-29, 1990.

  • 1. "Small for dates crown rump length and sac size predictive of spontaneous abortion despite fetal viability."

    2. "Comparison of techniques for ovulation induction in women with hypergonadotropic amenorrhea."

    •

    53. Thirty Eight Annual Clinical Meeting Of The American College Of Obstetricians and Gynecologists, San Francisco, California, May 7-10, 1990.

  • 1. "Ipsilateral versus contralateral ovary selection for dominant follicle in succeeding cycle."

    2. "Decreased preterm delivery with natural progesterone."

    •

    54. The 7th Reinier DeGraaf Symposium, Maastricht, The Netherlands, May 30 - June 2, 1990.

  • "Evidence for the existence of a pure corpus luteum deficiency."
    •

    55. 2nd International Meeting of Andrology, Diagnosing Male Infertility - New Possibilities And Limits, Tremezzo (Como), Italy, June 1-2, 1990.

  • 1. "Subtle motility abnormalities diagnosed by computer assisted semen analysis not found to correlate with fertile males better than conventional analysis."

    2. "Evaluation of the Kruger strict method for sperm morphology in predicting infertile males."

    3. "Correlation of male subfertility with low hypo-osmotic swelling scores even when the semen analysis is normal."

    4. "The use of therapeutic insemination to demonstrate the inadequacy of present WHO standards for normal motile density in distinguishing fertile from nonfertile males.

    5. "Determination of the clinical significance of antisperm antibodies using an in vitro insemination technique."

    6. "Endpoint of first stage zona pellucida-induced acrosome reaction in mouse spermatozoa characterized by acrosomal H+ and Ca2+ permeability: a possible model for the human sperm."

    •

    56. International Symposium of Assisted Reproductive Technology/Andrology (ARTA) 1990, Malaga, Spain, June 21-23, 1990.

  • 1. "Male factors in unexplained infertility."

    2. "Sex preselection: laboratory methods."

    3. "Cryopreservation of 2-8 cell human embryos."

    4. "Improving fertility potential of retrograde ejaculates."

    5. "Semen analysis for ARTA: Techniques/pitfalls

    6. "Poor hypo-osmotic swelling test results from cryopreserved-thawed sperm despite preservation of sperm motility."

    7. "The use of donor sperm as a probe to uncover subfertility even in males with normal motile density."

    8. "Motility as a predictor of fertility potential of human spermatozoa."

    9. "The use of the Kruger strict criteria of sperm morphology in non-IVF cycles."

    10. "Effect of advancing age on semen parameters."

    11. "The usefulness of the immunobead assay in evaluating male factor and cervical factor for antisperm antibodies."

    •

    57. VII World Congress On Human Reproduction, Helsinki, Finland, June 26-July 1, 1990.

  • 1. "Correlation of serum progestogen associated endometrial protein levels with endometrial biopsies, serum steroid levels, and therapy for luteal phase defects."

    2. "Efficacy of intrauterine insemination versus sexual relations versus intracervical insemination for treatment of cervical factor."

    •

    58. American Society for the Immunology of Reproduction (ASIR), Chicago, Illinois, June 20-23, 1990.

  • "The effect of antisperm antibodies in the male semen quality, post-coital results and pregnancy outcome.
    •

    59. European Society of Human Reproduction and Embryology, 90, European Sterility Congress Organization, II Joint Meeting, August 29th - September 1st, 1990, Milan-Italy.

  • "Periderm abnormalities may be predicted by elevated CA-125 levels during first few weeks following conception"

    "Sonographic clues to predict subsequent intrauterine fetal demise despite demonstration of viability at eight weeks"

    •

    60. III World Conference on Fallopian Tube in Health and Disease, Kiel, West Germany, July 3-6, 1990.

    1. "Serum progesterone and 17-hydroxyprogesterone in the diagnosis of ectopic pregnancies.

    2. "Poor correlation of positive chlamydia trachomatis antibody test and infertility in a middle class population."

    61. American Fertility Society 46th Annual Meeting, Washington, D.C., October 13-18, 1990.

  • 1. "A guanine nucleotide-binding regulatory protein in human sperm mediates acrosomal exocytosis induced by the human zona pellucida."

    2. "Results of cryopreservation of human embryos using a modified one-step method."

    3. "Evidence supporting the hyperstimulation regimen as a negative factor for in vitro fertilization pregnancies."

    •

    62. 34th Pan American Conference on Fertility and Sterility, Antigua, West Indies, January 26 - February 2, 1991.

  • 1. "Intrauterine insemination without hyperstimulation: Is it useful in infertility cases?"

    2. "Can untreated luteal phase defects lead to a higher rate of pre-term deliveries?"

    Panel Discussion Symposium

    1. Follicle Stimulation: When and How, or Why Bother?

    •

    63. Pacific Coast Fertility Society, Indian Wells, California, April 10-14, 1991.

  • 1. "Influence of sonographically determined endometrial thickness and growth on pregnancy rates in IVF-ET cycles."

    2. "Effects of follicle stimulating drugs on serum androgen levels and subsequent consequences on pregnancy rate."

    3. "The effect of the short follicular phase on subsequent conception."

    4. "Comparison of the effect of a long vs ultra-short gonadotropin releasing hormone regimen on IVF-ET statistics."

    5. Luteal phase support: Comparison of high and low dose progesterone therapy on pregnancy rates in an in vitro fertilization program."

    •

    64. American Society of Andrology, 1991 Annual Meeting, Montreal, Canada, April 27-30, 1991.

  • 1. "Detrimental effect of cryopreservation on human sperm viability."

    2. "The use of the Kruger Strict test for sperm morphology in distinguishing the fertile from subfertile male."

    3. "Motile density levels distinguishing fertile from subfertile males."

    4. "The effect of clomiphene citrate on sperm morphology."

    •

    65. Thirty ninth Annual Clinical Meeting of the American College of Obstetrics and Gynecologists, New Orleans, Louisiana, May 6-9, 1991.

  • 1. "Elevation of first trimester 17-hydroxyprogesterone levels despite the absence of corpora lutea."
    •

    66. 7th Workshop on Multiple Pregnancy, Berlin, May 30-June 1, 1991.

  • "A conservative treatment protocol with human menopausal gonadotropins aimed at reducing multiple births"

    "The effects of multiple gestation and selective reduction on fetal outcome"

    "Fetal outcome in patients whose uteri have decreased volume (2 case reports)"

    •

    67. Assisted Reproductive Technology/Andrology, Animal Reproduction and Nordic Society for Reproduction in Farm/Pet Animals, June 24-26, 1991, Copenhagen, Denmark.

  • 1. "Comparison of pregnancy rates following a 3 day follicular phase short leuprolide acetate hyperstimulation regimen to the traditional long leuprolide (luteal phase) protocol"

    2. "Measurement of 17-hydroxyprogesterone levels during the first trimester of donor oocyte pregnancies"

    3. "Cryopreservation of human embryos using a shorter cooling program and a single step removal of cryoprotectant during thawing"

    4. Increased endometrial thickness at time of hCG is associated with an increased pregnancy rate following IVF-ET and a leuprolide-acetate-hMG hyperstimulation protocol"

    5. "Comparison of pregnancy rates in donors and recipients using the same pool of oocytes"

    6. "A randomized prospective study comparing the influence of two different dosages of luteal phase progesterone therapy on pregnancy and abortion rates following IVF-ET"

    7. "The donor oocyte program - what it can teach us about the semen analysis as a predictor of fertilization"

    8. "An evaluation of women with zero percent fertilization in an in vitro fertilization program"

    9. "The evaluation of sperm morphology using Kruger's strict criteria"

    10 "Effect of antisperm antibodies on the computerized semen analysis"

    11 "Effect of swim-up, Percoll, and Sephadex sperm separation methods on the hypo-swelling test"

    12 "Some insight as to why cryopreserved sperm may have reduced fertility potential and attempts to improve it"

    13 "Evidence for the existence of a cryo-labile motility enhancing factor in human seminal plasma"

    14. "The effect of antisperm antibodies on post-coital results and the effect of intrauterine insemination on pregnancy outcome"

    15. "The importance of semen parameters and the use of IVF-ET to identify male factor"

    •

    68. 7th Annual Meeting of the European Society of Human Reproduction and Embryology, Paris, France, June 28-30, 1991.

  • 1. "Comparison of first trimester serum estradiol levels in aborters versus non-aborters"

    2. "Effect of swim-up, Percoll, and Sephadex sperm separation methods on the hypoosmotic swelling test"

    3. "The effect of follicle maturing drugs on influencing side of ovulation on succeeding cycles"

    •

    69. 7th World Congress on In Vitro Fertilization and Assisted Procreations, Paris, France, June 30-July 3, 1991.

  • 1. "An evaluation of women with zero percent fertilization in an in vitro fertilization program"

    2. "Comparison of pregnancy rates following a 3 day follicular phase short leuprolide acetate hyperstimulation regimen to the traditional long leuprolide (luteal phase) protocol"

    3. "Measurement of 17-hydroxyprogesterone levels during the first trimester of donor oocyte pregnancies"

    4. "Cryopreservation of human embryos using a shorter cooling program and a single step removal of cryoprotectant during thawing"

    5. "Comparison of pregnancy rates in donors and recipients using the same pool of oocytes"

    6. "A randomized prospective study comparing the influence of two different dosages of luteal phase progesterone therapy on pregnancy and abortion rates following IVF-ET"

    7. "The donor oocyte program - what it can teach us about the semen analysis as a predictor of fertilization"

    8. "Increased endometrial thickness at time of hCG is associated with an increased pregnancy rate following IVF-ET and a leuprolide-acetate hMG hyperstimulation protocol"

    •

    70. The American Fertility Society, Orlando, Florida, October 19-24, 1991.

  • 1. "Comparison of androgen and other hormone levels throughout the IVF cycle in pregnant vs nonpregnant patients"

    2. "A randomized prospective study comparing pregnancy rates following clomiphene citrate or human menopausal gonadotropin therapy"

    3. "Analysis of serum hCG levels in normal, singleton, multiple and abnormal pregnancies"

    •

    71. Women's Health Care in the 90's, Lake Buena Vista, Florida, February 16-19, 1992

  • 1. "Modern Methods of Diagnosing and Treating Ovulation Disorders"

    2. "Male Factor Infertility - What Role Does the Female Partner Play"

    •

    72. 39th Annual Meeting of the Society for Gynecologic Investigation, San Antonio, Texas, March 18-21, 1992.

  • 1. "Evidence for a paracrine interaction between progesterone and hCG secretion in the first trimester placenta"
    •

    73. American Society of Andrology, 1992 Annual Meeting, Bethesda, Maryland, March 27-30, 1992

  • 1. "Comparison of a rapid cryopreservation technique using test-yolk buffer to the standard procedure on semen parameters"

    2. "Comparison of human seminal plasma versus human tubal fluid media on the motility of cryopreserved thawed sperm"

    3. "Effect of percoll discontinuous density gradients vs spermprepTMII vs sephadex gel filtration on semen parameters"

    4. "Comparison of modified swim-up, mini percoll and sephadex G-10 sperm washing procedure on semen parameters"

    •

    74. 40th Annual Meeting of the Pacific Coast Fertility Society, Indian Wells, California, April 8-12, 1992.

  • 1. "The effect of clomiphene citrate therapy on post coital tests in successive treatment cycles and the response to estrogen therapy"

    2. "The effect of endometrial thickness and echo pattern on IVF outcome in donor oocyte-embryo transfer cycles"

    3. "The use of a short course of leuprolide acetate vs hCG to release oocytes in hMG treated women"

    4. "Inhibitory effect of insulin on hCG secretion in the first trimester placenta in vitro"

    5. "Anticarcinogenic and antimutagenic potential of the placenta in vitro in the first trimester"

    6. "Effect of progesterone replacement in the luteal phase in women without follicular maturing drugs on the corpus luteum function"

    •

    75. 40th Annual Clinical Meeting of the American College of Obstetricians and Gynecologists, Las Vegas, Nevada, April 26 - April 30, 1992

  • 1. "Options for preventing complications from high order multiple gestations resulting from hMG therapy"
    •

    76. Second International Capri Conference, Neuroendocrine and Peripheral Disorders of Female Reproductive System: Pathophysiology and Therapies, Capri, Italy May 22-26, 1992.

  • 1. "Comparison of hCG vs GnRH-analog in releasing oocytes following ultra-low dose gonadotropin stimulation."
    •

    77. The Proceedings of the 3rd World Congress on Endometriosis, Brussels, Belgium, June 1-3, 1992.

  • 1. "The relationship of CA-125 throughout the menstrual cycle and endometriosis"
    •

    78. 8th Annual Meeting of the European Society of Human Reproduction and Embryology, Hague, Netherlands, July 5-8, 1992

  • 1. "Stability of the hypo-osmotic swelling test over time"

    2. "The relationship of sperm motile density, strict morphology and HOS scores to pregnancy and fertilization rates in IVF-ET"

    3. "A prospective study to evaluate the efficacy of modified swim-up preparation for male sex selection"

    •

    79. 20th World Congress of Medical Technology, Ireland, July 26-31, 1992.

  • 1. "Membrane based RIA versus automated MEIA for the detection of IgG antibodies to cytomegalovirus"
    •

    80. ARTA Twin Conferences, Tossa de Mar, Costa de Bravo, Spain, August 18-20, 1992

  • 1. "Role of progesterone in prevention of early pregnancy loss and supportive implantation"

    2. "Pregnancy rates in donors/recipients using the same pool of oocytes"

    3. "Pregnancy rate and outcome of embryo transfer: Dorsal lithotomy vs knee-chest position: A randomized prospective study"

    4. "Effect of fresh seminal plasma on cryopreserved thawed sperm on motility/HOST"

    5. "Pregnancy rates using different hormonal stimulations for frozen embryo replacement cycles"

    6. "Rapid cryopreservation technique using test yolk buffer to the standard procedure/semen parameters"

    7. "The role of endometrial thickness in predicting IVF success"

    8. "Hypo-osmotic swelling test (HOS): its stability/reproducability over time"

    •

    81. ARTA Twin Conferences, Munich, Germany, August 22-23, 1992

  • 1. "Role of semen parameters in predicting fertilization/pregnancy outcome following IVF"

    2. "Effect of serum sperm antibodies in women on embryo quality/pregnancy outcome following IVF a controlled study"

    3. "Comparative role of GnRH in pituitary/placental gonadotropin section"

    4. "Diabetic like conditions modify the endocrine function of first trimester human placenta in vitro"

    5. "Comparative effects of GnRH/cAMP on hCG secretion by placental explants in dynamic and static cultures"

    6. "Election to be a donor in a shared oocyte program"

    7. "Therapeutic IUI for cervical factor: a controlled evaluation"

    8. "Effect of maternal cigarette smoking on placental secretion in vitro"

    9. "Metabolism of xenobiotics in human placentas of early pregnancy"

    •

    82. Ninth International Congress of Endocrinology, Nice, France, August 30 - September 5, 1992

  • 1. "Spontaneous ovulation and successful pregnancy despite bilateral streaked ovaries"

    2. "The effect of the age of the recipient on pregnancy rates following donor oocyte replacement"

    3. "Correlation between midcycle LH with estradiol and progesterone levels in natural cycles"

    •

    83. 5th International Congress of Reproductive Immunology, Rome, Italy, August 31 - September 3, 1992

  • 1. "The frequency of antisperm antibodies on the cervical mucus of women with poor post-coital tests and their effect on pregnancy rates"

    2. "The value of addition of progesterone therapy to leukocyte immunization for the prevention of the spontaneous abortion in primary aborters"

    3. "Effect of test yolk buffer on eluting antisperm antibodies from the sperm"

    4. "The effect of positive sera antisperm antibodies on in vitro pregnancy and spontaneous abortion rates"

    •

    84. 48th Annual Meeting of the American Fertility Society, New Orleans, Louisiana, October 31 - November 5, 1992

  • 1. "The effect of retinoic acid and its teratogenic derivatives on hCG secretion by the first trimester placenta in vitro"

    2. "Effect of age of oocyte donors on pregnancy rates in a shared-oocyte in vitro fertilization (IVF) program"

    3. "The influence of the serum progesterone level at the time of hCG on subsequent pregnancy rates from in vitro fertilization-embryo transfer (IVF-ET)"

    •

    85. The American College of Obstetricians and Gynecologists 1992 District III Annual Meeting, Costa del Sol, Spain, November 9-13, 1992

  • 1. "The correlation of pregnancy rates with endometrial thickness and endometrial echo patterns prior to hCG following various controlled hyperstimulation regimens"

    2. "A retrospective study to investigate the relationship of elapsed time between hCG injection to retrieval of first oocyte in IVF-ET to IVF outcome"

    86. XIV World Congress on Fertility and Sterility, Caracas, Venezuela, November 22-27, 1992.

    1. "A simplified method for cyropreservation of human embryos"

    2. "Can abnormal semen parameters truly identify the subfertile male"

    3. "The use of ultrasound to predict late first and early second trimester spontaneous abortions despite prior viability demonstrated"

    4. "Monitoring pre-transfer endometrial thickness and sonographic echo pattern useful in improving in vitro fertilization (IVF) pregnancy rates"

    5. "The importance of the luteinized unruptured follicle (LUF) syndrome as a complication of gonadotropin therapy"

    6. "A study of failed fertilization following IVF using both donor sperm and oocyte probe"

    7. "Comparison of pregnancy rates in donors vs recipients in a shared oocyte program"

    8. "Estradiol deficiency associated with spontaneous abortion even when adequate progesterone levels are maintained"

    9. "Diagnostic importance of serum CA-125 in non-malignant disorders"

    •

    87. New Concepts in Maternal Fetal Medicine, Gynecologic Oncology, & Reproductive Endocrinology and Infertility. Cooper Hospital University Medical Center, Camden, New Jersey, March 7, 1993.

  • 1. "The use of sonography and hormonal assays in the diagnosis and treatment of ovulatory disorders"
    •

    88. Beringer Research and Development, Indianapolis, Indiana, March 8, 1993.

  • 1. "Importance of hormonal assays in different aspects of reproductive endocrinology"
    •

    89. Insights Into Infertility - A Resolve/Serono Symposium for Patients and Health Professionals Concerned with Infertility Issues. Thomas Jefferson Alumni Hall, Philadelphia, Pennsylvania, March 21, 1993

  • 1. "Ovulation Dysfunction and Induction"
    •

    90. VII World Congress on Human Reproduction, Bali, Indonesia, April 4-9, 1993

  • 1. "The relationship of the luteinized unruptured follicle syndrome with the serum progesterone level at the time of hCG administration"

    2. "Premature luteinization as a cause of infertility in unstimulated cycles"

    3. "Aggressive treatment with high dose progesterone in women with very low first trimester progesterone levels may salvage a majority of "inevitable spontaneous abortions"

    4. "To evaluate whether the availability of intrauterine insemination (IUI) improves pregnancy rates with clomiphene citrate to comparable rates for gonadotropin therapy"

    5. "A randomized prospective study comparing pregnancy rates following treatment of luteal phase deficiency with either follicle maturing drugs or luteal phase support with progesterone"

    6. "Does a higher serum progesterone level at the time of hCG reduce IVF-ET pregnancy rates?"

    7. "Evidence that mild endometriosis is not a cause of spontaneous abortion (SAB)"

    8. "A randomized study to evaluate whether surgical removal of stage I and stage II endometriotic implants improves fertility rates"

    9. "Usefulness of placental protein 14 (PP14) as a replacement for the endometrial biopsy"

    10. "The use of gonadotropin releasing hormone agonists (GnRHa) for oocyte release in gonadotropin treated patients"

    11. "The importance of sonographic determination of endometrial thickness (ET) and echo patterns in IVF-ET"

    12. "Effect of natural cycles vs estrogen replacement vs follicle maturing drugs on pregnancy rates in frozen embryo transfer"

    13. "Effect of a 3 day course of a GnRH agonist on inhibiting premature luteinization (PL) in IVF-ET"

    14. "Correlation of FSH measurement by chemiluminescence vs radioimmunoassay method"

    15. "Antisperm antibody (ASA) in the female not associated with an increased risk of spontaneous abortions (SAB)"

    16. "The relationship of elapsed time (ETM) between hCG injection to oocyte retrieval to IVF outcome"

    17. "Decreased spontaneous abortion rate in progesterone treated women given leukocyte immunization"

    18. "Treatment of women with hyperprolactinemia and luteal phase defects"

    19. "The clinical effects of positive antisperm antibodies (ASA) in cervical mucus"

    20. "Pregnancy and spontaneous abortion rates in women with septate uteri transected by a new laser technique (Neodymium-YAG laser)"

    •

    91. 1993 Annual Pacific Coast Fertility Society Meeting, Indian Wells, California, April 14-18, 1993

  • 1. "Embryo transfer techniques as a cause of ectopic pregnancy in in vitro fertilization"

    2. "The use of a shared-donor oocyte program to evaluate the effect of uterine senescence"

    3. "Progesterone levels prior to hCG determined by RIA method superior to enzyme immunoassay method in predicting which IVF patients are more likely to conceive"

    4. "A prospective study comparing a 36 vs 38 hour time interval from hCG to oocyte retrieval on subsequent pregnancy rates"

    5. "Evaluation of stability of decline of pregnancy rate with succeeding cycles of IVF-ET as determined by cumulative probability of pregnancy"

    6. "Evaluation of whether using hCG to stimulate oocyte release helps or decreases pregnancy rates following intrauterine insemination"

    7. "Comparison of pregnancy rates among donors and recipients according to the serum progesterone level at time of hCG in a shared-oocyte IVF program"

    8. "The relationship of endometrial thickness and echo patterns and pregnancy rates in non-IVF cycles"

    9. "Adverse effect of a homogeneous hyperechogenic endometrial sonographic pattern on IVF-ET pregnancy rates"

    10. "Comparison of IVF outcome following the flare-up vs clomiphene citrate-hMG controlled ovarian hyperstimulation protocols for poor responders: A prospective study"

    •

    92. 1993 Annual American Society of Andrology Meeting, Tampa, Florida, April 16-19, 1993.

  • 1. "Male female sex ratio in births resulting from IVF according to swim-up vs percoll preparation of inseminated sperm"

    2. "The efficacy of intrauterine insemination for cervical and male factor without superovulation"

    3. "Comparison of sperm treatments for men with antisperm antibodies"

    4. "Comparison of post-thaw semen parameters of sperm separated from seminal plasma by either percoll or sephadex G-15 (sperm prep II) prior to freezing vs non-separated frozen sperm"

    5. "Evaluation of trehalose and proline as natural cryoprotectants of human sperm"

    6. "Comparison of a rapid vs conventional freezing method on the semen parameters of sperm that have been separated by percoll prior to freezing.

    93. Vth International Congress of Andrology, Tokyo, Japan, May 2-61, 1993.

    1. "Test yolk buffer fails to reduce levels of antisperm antibodies as measured by immunobead test"

    2. "Attempts to improve the quality of cryopreserved thawed sperm"

    3. "Effect of various sperm separation techniques on semen parameters and on functional integrity of sperm membrane"

    4. "Correlation of hypo-osmotic swelling results and pregnancy outcome"

    5. "Evaluation of sperm preparation techniques for men with antisperm antibodies"

    6. "Poor correlation of sperm morphology using strict criteria with either in vivo or in vitro pregnancy rates"

    7. "Poor correlation of motile sperm density with pregnancy rates in vivo and in vitro"

    8. "Evaluation of antisperm antibodies in women with poor post-coital results"

    9. "The treatment of male subfertility with fresh seminal plasma"

    10. "A highly effective simple technique for achieving male sex pre-selection"

    •

    94. Forty-First Annual Clinical Meeting of the American College of Obstetricians and Gynecologists, Washington, D.C., May 3-6, 1993.

  • 1. "The importance of daily periovulatory sera progesterone levels in addition to LH levels for better prediction of time of ovulation for intrauterine insemination"

    2. "The relationship of endometrial thickness with pregnancy rates in frozen embryo transfer cycles"

    3. "A challenge to the concept of "tubal reflux" to explain the rise and fall of serum CA-125 during the first trimester"

    •

    95. 75 Annual Meeting of the Endocrine Society, Las Vegas, Nevada, June 9-12, 1993.

  • 1. "Mid-cycle steroidal levels following ultra-low dose pure FSH stimulation versus combined FSH-LH stimulation"
    •

    96. The Triggering of Ovulation in Stimulated Cycles: hCG or LH? Bordeaux, France, June 19-20, 1993.

  • 1. "The use of leuprolide acetate for oocyte release and advancement of meiosis in gonadotropin stimulated cycles"
    •

    97. 9th Annual Meeting of the European Society of Human Reproduction and Embryology, Thessaloniki, Greece, June 27-30, 1993.

  • 1. "Effect of natural antioxidants tocopherol and ascorbic acid in maintenance of sperm activity during freeze-thaw process"

    2. "The use of IVF-ET pregnancies from patients with tubal occlusion to help determine the etiology for the increase in first trimester CA-125 levels"

    3. "The relationship of mid-cycle steroids and follicle diameter as determined by pregnancy cycles following a single intrauterine insemination"

    4. "Pregnancies following in vitro fertilization (IVF) in women with high early follicular phase FSH levels without donor oocytes"

    5. "Comparison of pregnancy rates by age of recipient in a shared oocyte program"

    6. "Reduced pregnancy rates following frozen embryo transfer into women with thinner endometrial"

    7. "Improved pregnancy rates after treating sperm positive for antisperm antibodies with chymotrypsin-galactose"

    8. "A platelet related pregnancy factor in diagnosis of early pregnancy"

    9. "The relationship of endometrial thickness and echo pattern to endometriosis"

    •

    98. Assisted Reproductive Technology/Andrology, Alicante, Spain, July 9-11, 1993.

  • 1. "New treatment for male factor secondary to antisperm antibodies"

    2. "A study to determine the ideal interval from hCG injection to retrieval to GnRHa hMG stimulated patients"

    3. "A method to increase y body sperm concentration and increase male offspring"

    4. "A modification of a bovine embryo freezing technique for human use: Pregnancy rates according to endometrial stimulation protocol"

    5. "Is intrauterine insemination a helpful treatment for male infertility?"

    6. "A controlled study to determine if fresh seminal plasma can improve the motility of frozen thawed sperm"

    7. "Can the reduction of glycerol through the use of other natural cryoprotectants improve semen parameters on cryopreserved thawed sperm"

    8. "Effect of different separation techniques to sperm cryopreservation on post-thaw semen parameters"

    9. "Rapid freezing technique results in better post-thaw semen parameters than conventional freezing on sperm separated by percoll prior to freezing"

    10. "Reduced pregnancy rates related to the aged uterus may be at least partly if not completely remediable"

    •

    99. 26th Annual Meeting for the Society for the Study of Reproduction, Fort Collins, Colorado, August 1-4, 1993.

  • 1. "Comparison of gonadotropin and steroidal hormone levels prior to human chorionic gonadotropin injection following controlled ovarian hyperstimulation with pure FSH vs human menopausal gonadotropins in patients down-regulated with leuprolide acetate"
    •

    100. 8th Reinier de Graaf Symposium, Amsterdam, Netherlands, September 2-4, 1993

  • 1. "Can in vitro fertilization be successful in women with elevated serum follicle stimulating hormone levels"
    •

    101. VIII World Congress on IVF and Alternate Assisted Reproduction, Kyoto, Japan, September 12-15, 1993.

  • 1. "Up to what age should a woman be allowed to donate oocytes in a shared oocyte IVF program"

    2. "Pregnancy rates using a rapid cryopreservation according to different hormonal replacement protocols.

    3. "Prediction of pregnancy rates according to serum progesterone (P) at the time of hCG according to methodology of measuring P (RIA vs non-isotopic method)".

    4. "Does the method of serum preparation for in vitro fertilization-embryo transfer (IVF-ET) influence the male female sex ratio".

    5. "Decreased pregnancy rates have been seen in patients having IVF-ET when the endometrial thickness was <10mm or a homogeneous hyperechogenic echo pattern was seen at the time of hCG injection".

    6. "Higher ectopic pregnancy rates associated with embryo transfer <15mm from fundus".

    7. "Certain endometrial echo pattern at time of human chorionic gonadotropin (hCG) associated with reduced pregnancy rates following in vitro fertilization".

    8. "Adverse effect of high serum progesterone (P) level at time of hCG on subsequent IVF pregnancy rates related to adverse effect on endometrium rather than oocytes as evidenced by shared donor oocyte program".

    9. "Factors influencing reduction in IVF pregnancy rates (PRs) in succeeding cycles using cumulative probability of pregnancy".

    10. "A prospective study to determine the appropriate time interval from hCG to retrieval in patients using leuprolide acetate-human menopausal gonadotropin controlled ovarian hyperstimulation".